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AG124000: α-D-GalNAc-Ethyl-AzideC10H18N4O6 290. 27 An D N acetylgalactosamine ( D GalNAc) ligand equipped with an azide functionalized linker through a short ethyl spacer. The terminal azide can be covalently coupled to alkyne partners via copper catalyzed azide alkyne cycloaddition (CuAAC), or to dibenzocyclooctyne (DBCO) and related strained alkynes using copper free click chemistry. This compound enables the construction of hepatocyte targeted therapeutics and research tools that

with applications in antibody-recruiting molecule and immunotherapy research

Boc-5-(2-Acetamido-2-deoxy-β-D-Galactopyranosyl-oxy) pentanoic acid

2-Acetylthioethyl β-D-glucopyranoside

β-D-Glc-Bu-CO2H

4-Carboxybutyl β-D-glucopyranoside

35 / An α-D-N-acetylgalactosamine (GalNAcα) ligand equipped with a methyl ester-protected carboxylic acid through a short butyl spacer

and in high-throughput screening formats

which can be removed by hydrogenolysis to reveal the free amine for conjugation

β-D-Lac-Pr-N3

providing a straightforward route to conjugate the glycan onto NHS-activated molecules and surfaces

Boc-5-Aminopentyl 2-acetamido-2-deoxy-β-D-galactopyranoside

GlcNAcβ(1-4)GlcNAc-β-NH-C3-NHCO-PEG4-DBCO