GA131030: Fmoc-Thr(Galβ(1-3)(GlcNAcβ(1-6))GalNAc-OH (Peracetate)

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Description

GA131030: Fmoc-Thr(Galβ(1-3)(GlcNAcβ(1-6))GalNAc-OH (Peracetate)C57H71N3O28 1246. 18 An Fmoc protected L threonine building block carrying a branched Gal1 3[GlcNAc1 6]GalNAc trisaccharide, designed for solid phase peptide synthesis (SPPS) of glycopeptides. The N Fmoc group is removed under standard base conditions (piperidine) during chain elongation, while the free carboxylic acid is available for coupling to the growing resin bound peptide. The sugar hydroxyl groups are protected as acetate esters (peracetate),

N-α-Fmoc-N-γ-(2-acetamido-2-deoxy-3

C2H34N2O14 / 526

Galβ1-4GlcNAc) building block

38 / A peracetylated β-D-N-acetylgalactosamine (GalNAcβ) ligand equipped with an azide-functionalized linker through a short ethyl spacer

2-O-sulfo-α-L-idopyranosyluronate-(1-4)-2-deoxy-2-sulfoamido-6-O-sulfo-α/β-D-glucopyranoside tetrasodium salt

25-Hydroxyvitamin D3 (26

α-D-Man-Et-SH

It is a substrate for sialyltransferases and fucosyltransferases

6-tetra-O-acetyl-β-D-glucopyranosyl)-L-tyrosine

Radsterin-d6

tetrasodium salt

/ Fmoc-Ser(Neu5Acα(2-6)GalNAc)-OH (Peracetate