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Description

GA231000: Fmoc-Thr(GlcNAc(Ac)3-β-D)-OHC33H38N2O13 670. 66 An Fmoc protected L threonine building block carrying a D GlcNAc residue, designed for solid phase peptide synthesis (SPPS) of glycopeptides. The N Fmoc group is removed under standard base conditions (piperidine) during chain elongation, while the free carboxylic acid is available for coupling to the growing resin bound peptide. The sugar hydroxyl groups are protected as three acetate esters (Ac3), which keep the glycan inert

144) / Mucin1

65 / / 1-α

The thiol group can be reacted with other thiol-modified substrates to form disulfide bonds

C10H20N2O6 / 264

/ IdoA-GlcNS

Fmoc-Asn(beta-D-Glc(Ac)4)-OH

α-D-GalNAc-Thr-NH-Biotin

4-Carboxybutyl N-acetyl-β-D-galactosamine

Fmoc-L-Thr(Man(Ac)4-α-D)-OH

N-Biotin-Thr(Galβ(1-3)GalNAc-α)-OH

T Antigen (Serine)

2-Azidoethyl α-D-galactopyranoside